BAG3-dependent expression of Mcl-1 confers resistance of mutant KRAS colon cancer cells to the HSP90 inhibitor AUY922
- Creator: Wang, Chun Yan , Guo, Su Tang , Croft, Amanda , Yan, Xu Guang , Jin, Lei , Zhang, Xu Dong , Jiang, Chen Chen
- Resource Type: journal article
- Date: 2018
Cooperativity of HOXA5 and STAT3 is critical for HDAC8 inhibition-mediated transcriptional Activation of PD-L1 in human melanoma cells
- Creator: Wang, Yu Fang , Liu, Fen , Sherwin, Simonne , Farrelly, Margaret , Yan, Xu Guang , Croft, Amanda , Liu, Tao , Jin, Lei , Zhang, Xu Dong , Jiang, Chen Chen
- Resource Type: journal article
- Date: 2018
Functional identification of a novel transcript variant of INPP4B in human colon and breast cancer cells
- Creator: Croft, Amanda , Guo, Su Tang , Sherwin, Simonne , Farrelly, Margaret , Yan, Xu Guang , Zhang, Xu Dong , Jiang, Chen Chen
- Resource Type: journal article
- Date: 2017
Reactive oxygen species dictate the apoptotic response of melanoma cells to TH588
- Creator: Wang, Jia Yu , Jin, Lei , La, Ting , McFarlane, Jennifer , Lei, Fu Xi , Tabatabaee, Hessam , Chen, Jie Zhong , Croft, Amanda , Jiang, Chen Chen , Zhang, Xu Dong , Yan, Xu Guang , Sherwin, Simonne , Farrelly, Margaret , Zhang, Yuan Yuan , Liu, Fen , Wang, Chun Yan , Guo, Su Tang , Yari, Hamed
- Resource Type: journal article
- Date: 2016
INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas
- Creator: Chi, Meng Na , Guo, Su Tang , Croft, Amanda , Hondermarck, Hubert , Scolyer, Richard A. , Jiang, Chen Chen , Zhang, Xu Dong , Wilmott, James S. , Guo, Xiang Yun , Yan, Xu Guang , Wang, Chun Yan , Liu, Xiao Ying , Jin, Lei , Tseng, Hsin-Yi , Liu, Tao
- Resource Type: journal article
- Date: 2015
RIP1 kinase is an oncogenic driver in melanoma
- Creator: Liu, Xiao Ying , Lai, Fritz , Jin, Lei , Zhang, Xu Dong , Yan, Xu Guang , Jiang, Chen Chen , Guo, Su Tang , Wang, Chun Yan , Croft, Amanda , Tseng, Hsin-Yi , Wilmott, James S. , Scolyer, Richard A.
- Resource Type: journal article
- Date: 2015
Oncogenic activation of MEK/ERK primes melanoma cells for adaptation to endoplasmic reticulum stress
- Creator: Croft, Amanda , Tay, Kwang H. , Zhang, Xu D. , Boyd, Suzanah C. , Guo, Su T. , Jiang, Chen C. , Lai, Fritz , Tseng, Hsin-Yi , Jin, Lei , Rizos, Helen , Hersey, Peter
- Resource Type: journal article
- Date: 2014
Sustained IRE1 and ATF6 signaling is important for survival of melanoma cells undergoing ER stress
- Creator: Tay, Kwang Hong , Luan, Qi , Croft, Amanda , Jiang, Chen Chen , Jin, Lei , Zhang, Xu Dong , Tseng, Hsin-Yi
- Resource Type: journal article
- Date: 2014
OBATOCLAX and ABT-737 induce ER stress responses in human melanoma cells that limit induction of apoptosis
- Creator: Wroblewski, David , Jiang, Chen Chen , Croft, Amanda , Farrelly, Margaret L. , Zhang, Xu Dong , Hersey, Peter
- Resource Type: journal article
- Date: 2013
Contrasting effects of Nutlin-3 on TRAIL- and Docetaxel-induced Apoptosis due to upregulation of TRAIL-R2 and Mcl-1 in human melanoma cells
- Creator: Tseng, Hsin-Yi , Jiang, Chen Chen , Croft, Amanda , Thorne, Rick Francis , Yang, Fan , Liu, Hao , Hersey, Peter , Zhang, Xu Dong
- Resource Type: journal article
- Date: 2010
2-Deoxy-D-glucose enhances TRAIL-induced apoptosis in human melanoma cells through XBP-1-mediated up-regulation of TRAIL-R2
- Creator: Liu, Hao , Jiang, Chen Chen , Lavis, Christopher J. , Croft, Amanda , Dong, Li , Tseng, Hsin-Yi , Yang, Fan , Tay, Kwang Hong , Hersey, Peter , Zhang, Xu Dong
- Resource Type: journal article
- Date: 2009